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Dasatinib is a cyp3a4 substrate; indinavir is a strong cyp3a4 inhibitor.
The change in indinavir pharmacokinetic parameters during pregnancy was less apparent when comparing with historical data in non-pregnant thai adults table 2 although median auc and c 12 h remained lower.
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Indinavir was well tolerated in phase i ii trials, although a few side effects were reported.
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Indinavir capsules are sensitive to moisture.
Eating grapefruit or drinking grapefruit juice while you are taking indinavir may increase the amount of indinavir in your blood, which may increase your risk for serious side effects.
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